(John 6: 35)
Some people never find God.
So they assume He doesn't exist.
Maybe in reality, they do not exist.
It's perfectly possible to drown-out God for your whole life. To accept the world's terms and the world's arguments: to play the game of life without God being a factor. We can always play the card of 'nature': funneling all of reality through the lens of our senses only. To play on these terms is to live only in and for the senses: in other words, a selfish life for and of pleasure and avoidance of pain, only.
But then your wife dies. Your child is born - it's Down's. Your car is crushed, your job ends, your pleasure sours, your life's a ruin. OR IS IT? A life that implodes when all seems lost is not life: just the end of the what you thought life was about. Suffering now brings enforced pondering, enforced reassessment. Maybe life is more than getting stuff, using stuff, and gratifying the ego (even through supposed relationships and 'higher' satisfactions).
In short, we have to go deeper. We have to allow God to shape us. We have to find God and He's to be found in the space within us known as the soul. The deepest truth about us lurks in the soul. For many, it's not a pretty place to visit. Since they never do, it's a surprise to find the soul at all. But then it's found to be full of dross and lies and smut and sin and death. Another reason to find God, who still loves us even in the midst of the soul's unswept state.
The soul is the God hole. Do you stuff it full of garbage or sweep it out and let God enter? Do you let God dwell inside your heart, mind, and soul, or do you 'believe in yourself' your whole life, missing thereby the point of life itself: to love God with all, commune with Him in joy, and radiate His love to others even as you love yourself aright? God is closer than we think; our deepest yearning is to know the Lord and be with Him forever.
But in lieu of finding the soul and finding God, there is a world of distractions to try out to plug that hole, which becomes a void. Entertainment, cranial pursuits, pleasures of the flesh, trivia, ambition, competition, wealth accumulation, knowledge, sport, family. food and drink, exercise, you name it. If you know a deep yearning that is not satisfied by the world's terms of play in this life, the world will tell you you're sick or mad. You are actually being called to something real and lasting: relationship with God: Father, Son, and Holy Spirit. Nothing else can satisfy the hole that God alone can fill, empower, grace, and balm. To make you whole and real and full of life and love.
Experiencing the hole is a call to prayer. Boundless ennui is God taking away worldly means in order to enable the ultimate and most important end: communion with Him. It really means He wants to be with us and to share His presence. It's a God telephone call, if you like. The only question is, do you want to know God personally or just carry on as though all the things that never satisfy deserve another million chances?